Benefits From Antidepressants
نویسندگان
چکیده
Data Extraction: Children’s Depression Rating Scale– Revised scores (youth population), Hamilton Depression Rating Scale scores (adult and geriatric populations), and estimated response and remission rates at 6 weeks were analyzed for 2635 adults, 960 geriatric patients, and 708 youths receiving fluoxetine and for 2421 adults receiving immediate-release venlafaxine and 2461 adults receiving extended-release venlafaxine.
منابع مشابه
Long-term antidepressant use: patient perspectives of benefits and adverse effects
Long-term antidepressant treatment has increased and there is evidence of adverse effects; however, little is known about patients' experiences and views of this form of treatment. This study used mixed methods to examine patients' views and experiences of long-term antidepressant treatment, including benefits and concerns. Data from 180 patients, who were long-term users of antidepressants (3-...
متن کاملPlacebo, prozac and PLoS: significant lessons for psychopharmacology.
Kirsch et al. (2008, Initial severity and antidepressant benefits: a meta-analysis of data submitted to the Food and Drug Administration. PLoS Med 5: e45), conducted a meta-analysis of data from 35 placebo controlled trials of four newer antidepressants. They concluded that while these drugs are statistically significantly superior to placebo in acute depression, the benefits are unlikely to be...
متن کاملANTINOCICEPTIVE A CTIVITY OF ANTIDEPRESSANTS AND CORRELATI ON WITH NEUROTRANSMITIER INHIBITORY POTENCY
Antidepressant agents inhibit the neuronal reuptake of monoamines such as serotonin (5-HT), noradrenaline (NA), and dopamine (DA). Several clinical and animal studies have advocated the use of these agents in the management of pain. In this study, therefore, the possibility of a correlation between the analgesic activity of six serotonin specific reuptake inhibitor (SSRI) antidepressants an...
متن کاملAntidepressants for irritable bowel syndrome.
Systematic reports of antidepressant use in irritable bowel syndrome (IBS) first appeared in the medical literature three decades ago. Recent meta-analyses of the cumulative controlled experience confirm the efficacy of antidepressants in IBS and other functional gastrointestinal disorders: only 3–4 patients require treatment to demonstrate a benefit over placebo—numbers indicating a solid trea...
متن کاملEffectiveness of antidepressants: an evidence myth constructed from a thousand randomized trials?
Antidepressants, in particular newer agents, are among the most widely prescribed medications worldwide with annual sales of billions of dollars. The introduction of these agents in the market has passed through seemingly strict regulatory control. Over a thousand randomized trials have been conducted with antidepressants. Statistically significant benefits have been repeatedly demonstrated and...
متن کاملSecond-generation antidepressants for depression in adults.
Evidence-Based Answer Second-generation antidepressants (antidepressants other than tricyclics and monoamine oxidase inhibitors) used to treat major depressive disorder in adults have similar effectiveness. However, some clinically significant differences among individual drugs exist with respect to onset of action and adverse effects, which may affect treatment choices. For example, mirtazapin...
متن کامل